Claudio Ortega, MD Director and Founder

Dr. Ortega has dedicated his career to clinical research. Prior to Intrials foundation in 1999, Dr. Ortega held Medical Affairs positions at Merrell-DOW; as Medical Director at Schering Brazil, being responsible for structuring of the company´s clinical research department.

In 1988, Dr. Ortega joined PRI RWJ (J&J) in Zurich as Clinical Research Director, with responsibilities in Europe for phase III trials in dermatology and CNS. From 1995 to 1998, Dr. Ortega became COVANCE representative in Brazil. His areas of expertise include genetics and rare diseases, oncology, dermatology, epilepsy, cardiovascular, antibiotics and women’s health.

Dr. Ortega has a medical degree from “Escola de Medicina da Santa Casa de São Paulo”, Brazil and a post-graduate degree in Genetics and Endocrinology at New York State University, Syracuse, NY.

He is the author of the textbook “Genética Médica – (or “Clinical genetics”, 1977), published in Portuguese for Brazilian medical students, of the chapter “Mucopolisacaridosis” in the textbook “Endocrine and Genetic Diseases of Childhood and Adolescence”, edited by Lytt Gardner (1975), as well as several articles in clinical genetics.

Sergio Lopes, Pharm.D

Dr. Lopes brings extensive experience in all key areas of product development and marketing, both with prescription and OTC products, nutritionals and medical devices. His in-depth knowledge of the health care and regulatory environment in Brazil are key contributions to INTRIALS’ successful record of accomplishment in obtaining quick regulatory approvals and importing processes.

Prior to founding INTRIALS, Dr. Lopes was General Manager of Bristol-Myers Squibb, Peru, and Marketing Director of Bristol-Myers Squibb, Brazil, having planned, directed and supervised studies in a number of therapeutic areas such as cardiology, CNS, dermatology, hematology, infectious diseases, ophthalmology, urology, oncology, respiratory, rheumatology and vaccines.

Dr. Lopes has Bachelor Degree in Pharmacy and Biochemistry from USP – Universidade de São Paulo, Brazil, a Pharm.D in Industrial Biochemistry and Pharmacy from the same Institution.

Gizele Thame, BMD, Ph.D

Prior to co-founding INTRIALS, Dr. Thame held several positions as researcher of Sao Paulo State Government, and was Member of the Scientific Commission of Adolfo Lutz Institute, São Paulo, Brazil. She has also participated in the “Clinical Research Audit” training program according to FDA rules in Pennsylvania, USA, in 1996.

Her extensive experience in basic research, combined with a significant educational background allowed her to develop the 23 courses in Clinical Research for the INTRIALS Continuing Education Program. These programs had contributed to the high professional level of INTRIALS’ staff, as well as to the professional development of

Dr. Thame received her Bachelor Degree in Biomedical Sciences from Universidade Metodista de Piracicaba, Brazil, her Masters Degree in Public Health from USP - Universidade de São Paulo, Brazil, and her Ph.D in Public Health from USP - Universidade de São Paulo, Brazil. She is the main author of 5 scientific articles published on prestigious indexed publications.